Back to the Great Outdoors: Speculative Realism as Philosophy of Science

This is an essay on Quentin Meillassoux' recent book After Finitude: An Essay on the Necessity of Contingency, placing it within recent discussions of the relationship between science, philosophy and the humanities. The book presents a strong critique of the linguistic turn in continental and analytic philosophy and argues for a retrieval of a realist notion of the power of reason. There are nonetheless a few remaining ontological problems identified towards the end of this review essay

Yoga jam: remixing Kirtan in the Art of Living

Yoga Jam are a group of musicians in the United Kingdom who are active members of the Art of Living, a transnational Hindu-derived meditation group. Yoga Jam organize events—also referred to as yoga raves and yoga remixes—that combine Hindu devotional songs (bhajans) and chants (mantras) with modern Western popular musical genres, such as soul, rock, and particularly electronic dance music. This hybrid music is often played in a clublike setting, and dancing is interspersed with yoga and meditation. Yoga jams are creative fusions of what at first sight seem to be two incompatible phenomena—modern electronic dance music culture and ancient yogic traditions. However, yoga jams make sense if the Durkheimian distinction between the sacred and the profane is challenged, and if tradition and modernity are not understood as existing in a sort of inverse relationship. This paper argues that yoga raves are authenticated through the somatic experience of the modern popular cultural phenomenon of clubbing combined with therapeutic yoga practices and validated by identifying this experience with a reimagined Vedic tradition

Metabolites of Purine Nucleoside Phosphorylase (NP) in Serum Have the Potential to Delineate Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma (PDAC), the fourth highest cause of cancer related deaths in the United States, has the most aggressive presentation resulting in a very short median survival time for the affected patients. Early detection of PDAC is confounded by lack of specific markers that has motivated the use of high throughput molecular approaches to delineate potential biomarkers. To pursue identification of a distinct marker, this study profiled the secretory proteome in 16 PDAC, 2 carcinoma in situ (CIS) and 7 benign patients using label-free mass spectrometry coupled to 1D-SDS-PAGE and Strong Cation-Exchange Chromatography (SCX). A total of 431 proteins were detected of which 56 were found to be significantly elevated in PDAC. Included in this differential set were Parkinson disease autosomal recessive, early onset 7 (PARK 7) and Alpha Synuclein (aSyn), both of which are known to be pathognomonic to Parkinson's disease as well as metabolic enzymes like Purine Nucleoside Phosphorylase (NP) which has been exploited as therapeutic target in cancers. Tissue Microarray analysis confirmed higher expression of aSyn and NP in ductal epithelia of pancreatic tumors compared to benign ducts. Furthermore, extent of both aSyn and NP staining positively correlated with tumor stage and perineural invasion while their intensity of staining correlated with the existence of metastatic lesions in the PDAC tissues. From the biomarker perspective, NP protein levels were higher in PDAC sera and furthermore serum levels of its downstream metabolites guanosine and adenosine were able to distinguish PDAC from benign in an unsupervised hierarchical classification model. Overall, this study for the first time describes elevated levels of aSyn in PDAC as well as highlights the potential of evaluating NP protein expression and levels of its downstream metabolites to develop a multiplex panel for non-invasive detection of PDAC

Identity, spatiality and postcolonial resistance:geographies of the tourism critique in Goa

This article maps some of the ways that the critique of tourism development in the Indian state of Goa is connected to Goan patriotism. Reactions against tourism in Goa assume a prior definition of ‘Goa’, and this definition is often patriotic. One of the central processes to understanding contemporary Goa’s identity politics in the face of tourism is its former colonisation by the Portuguese. Treating the tourism critique in Goa as a geographically and historically specific discourse in this article means discussing four aspects of what will be called its spatiality: geopolitics, geohistories/disembeddings, socio-spatial biases and situatedness. It will be argued that the spatiality of the tourism critique shows that its connection to patriotism is not straightforward and immediate, but contingent. It will also be argued that although the spatiality of the tourism critique points to its heterogeneity, it is precisely because there are multiple constructions of ‘Goa’ and ‘Goan identity’ that the discourse constitutes its object, Goa

A geophilosophy to come

Review of Ian Buchanan and Gregg Lambert, eds. Deleuze and Spac

Trance and visibility at dawn:racial dynamics in Goa's rave scene

The geography of music has recently turned to questions of embodiment and materiality to account for the sensuous specificity of music. Extending this work, this article emphasizes the constitutive work that embodied experience of music and space does for social differences such as race and gender. It criticizes what is perceived as a limited conception of embodiment in non-representational theory. Using ethnographic evidence from the rave tourism scene in Goa, India, it is argued that precisely during the scene's most mystical and hedonistic moments (what will be called the ‘morning phase'), racial dynamics are at their starkest. It is crucial to understand that racial difference is emergent and not automatic. The article then suggests a Deleuzian musicology which conceives music not as form, language or ideology, but as force. Accounting for the richness of musical materiality involves examining the networks of power and inequality through which it necessarily operates

Music, space, identity:geographies of youth culture in Bangalore

This article begins from a perceived lack of empirical evidence in cultural studies, namely the ethnography of cultural globalization in ‘global cities’ other than those of the West. Youth culture among the upper strata of the South-Indian metropolis Bangalore is taken as an instance of how mod- ernity is experienced and produced in the post-colonial Third World. The focus lies on the reception of Western pop music, but music is treated broadly as a practice situated in, and producing, real and imagined space. Two examples of these musical practices serve to elaborate on Indian power relations, Indian modernity and the critical geography of music